The impact of a low dose, low volume, multi-site immunization on the production of therapeutic antivenoms in Thailand

• Main Authors: Supod Sriprapat, Surasak Aeksowan, Sompong Sapsutthipas, Charoonroj Chotwiwatthanakun, Porntip Suttijitpaisal, Ronachai Pratanaphon, Orawan Khow, Visith Sitprija, Kavi Ratanabanangkoon
• Other Authors: Queen Saovabha Memorial Institute
• Format: Article
• Published: 2018
• Subjects: Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/21037
• Institution: Mahidol University

Therapeutic antivenom against snakes was first produced by Albert Calmette in 1894. Since then antivenoms have saved the life of countless snakebite victims. However, there are still many problems associated with antivenom production, for example variable percentage of responder horses, low neutrali...