The purine salvage enzyme hypoxanthine guanine xanthine phosphoribosyl transferase is a major target antigen for cell-mediated immunity to malaria

• Main Authors: Morris O. Makobongo, George Riding, Huji Xu, Chakrit Hirunpetcharat, Dianne Keough, John De Jersey, Peter Willadsent, Michael F. Good
• Other Authors: Royal Brisbane Hospital
• Format: Article
• Published: 2018
• Subjects: Multidisciplinary
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/21050
• Institution: Mahidol University

Although there is good evidence that Immun. to the blood stages of malaria parasites can be mediated by different effector components of the adaptive immune system, target antigens for a Prin. component, effector CD4+ T cells, have never been defined. We generated CD4+ T cell lines to fractions of n...