HIV-1 neutralization by monoclonal antibody against conserved region 2 and patterns of epitope exposure on the surface of native viruses

Background: Conserved neutralizing epitopes are considered to be a key role for eliciting broadly neutralizing antibody (NAb). Previously, two conserved neutralizing epitopes of HIV-1 CRF01_AE envelope were identified at amino acid 93-112 of the C1 (C1E) and at 218-239 of the C2 (C2E) regions. To...

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Bibliographic Details
Main Authors: Apichai Sreepian, Jongruk Permmongkol, Wannee Kantakamalakul, Sontana Siritantikorn, Nattaya Tanlieng, Ruengpung Sutthent
Format: Article
Language:English
Published: BioMed Central 2012
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/2109
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Institution: Mahidol University
Language: English