Interleukin-10 induces uteroglobin-related protein (UGRP) 1 gene expression in lung epithelial cells through homeodomain transcription factor T/EBP/NKX2.1

• Main Authors: Achara Srisodsai, Reiko Kurotani, Yoshihiko Chiba, Faruk Sheikh, Howard A. Young, Raymond P. Donnelly, Shioko Kimura
• Other Authors: National Cancer Institute
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/21108
• Institution: Mahidol University

UGRP1 is a downstream target gene for homeodomain transcription factor T/EBP/NKX2.1, which is predominantly expressed in lung epithelial cells, and may play an anti-inflammatory role in lung inflammation. To understand the role of UGRP1 in inflammation, its expression was investigated in relation to...