Cardiac mitochondrial damage and biogenesis in a chronic model of type 1 diabetes

• Main Authors: Xia Shen, Shirong Zheng, Visith Thongboonkerd, Ming Xu, William M. Pierce, Jon B. Klein, Paul N. Epstein
• Other Authors: University of Louisville
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/21130
• Institution: Mahidol University

Diabetic cardiomyopathy is a common complication leading to heightened risk of heart failure and death. In the present report, we performed proteomic analysis on total cardiac proteins from the OVE26 mouse model of type 1 diabetes to identify protein changes that may contribute to diabetic cardiomyo...