Immunostimulatory CpG oligodeoxynucleotide confers protection in a murine model of infection with Burkholderia pseudomallei

• Main Authors: Surasakdi Wongratanacheewin, Wannapa Kespichayawattana, Pakamas Intachote, Sathit Pichyangkul, Rasana W. Sermswan, Arthur M. Krieg, Stitaya Sirisinha
• Other Authors: Khon Kaen University
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/21367
• Institution: Mahidol University

Although CpG oligodeoxynucleotides (CpG ODNs) are known to enhance resistance against infection in a number of animal models, little is known about the CpG-induced protection against acute fatal sepsis such as that associated with the highly virulent bacterium Burkholderia pseudomallei. We previousl...