Molecular pathways executing the "trophic sentinel" response in HPV-16 E7-expressing normal human diploid fibroblasts upon growth factor deprivation

In response to oncogenic insults, normal human cells execute a defense response that culminates in cellular suicide, apoptosis. Normal human diploid fibroblasts expressing the human papillomavirus type 16 (HPV-16) E7 oncoprotein are predisposed to apoptosis when they are deprived of growth factors....

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Bibliographic Details
Main Authors: Alexandra Eichten, Debrah S. Rud, Miranda Grace, Siribang On Piboonniyom, Valerie Zacny, Karl Münger
Other Authors: Harvard Medical School
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/21403
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Institution: Mahidol University

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