The pharmacodynamic study of a potent new antimalarial (MC<inf>1</inf>)

2,3-bis(Trifluoromethyl)-4-(3-hydroxyquinuclidinylquinoline) or MC1is a new synthetic compound with potent antimalarial activity in vitro and in vivo studies. The IC50values of MC1and chloroquine in in vitro culture of Plasmodium falciparum are 7.0×10-8and 6.06×10-7M, respectively. In an in vivo stu...

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Bibliographic Details
Main Authors: Jutamaad Satayavivad, Piyachit Watcharasit, Pattaya Khamkong, Jantamas Tuntawiroon, Chikavee Pavaro, Somsak Ruchirawat
Other Authors: Chulabhorn Research Institute
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/21417
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Institution: Mahidol University