A potential role of interleukin 18 in severe falciparum malaria

Interleukin-18 (IL-18) is a potent proinflammatory cytokine that induces interferon-γ (IFN-γ) production from Th1 cells, NK cells and activated macrophages, particularly in the presence of IL-12. However, it is also shown that without help from IL-12, IL-18 is capable of inducing IL-4 and IL-13 prod...

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Bibliographic Details
Main Authors: Somei Kojima, Yukiko Nagamine, Masashi Hayano, Sornchai Looareesuwan, Kenji Nakanishi
Other Authors: Institute of Medical Science The University of Tokyo
Format: Review
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/21424
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Institution: Mahidol University