In vivo assessment of drug efficacy against Plasmodium falciparum malaria: Duration of follow-up

• Main Authors: Kasia Stepniewska, Walter R.J. Taylor, Mayfong Mayxay, Ric Price, Frank Smithuis, Jean Paul Guthmann, Karen Barnes, Hla Yin Myint, Martin Adjuik, Piero Olliaro, Sasithon Pukrittayakamee, Sornchai Looareesuwan, Tran Tinh Hien, Jeremy Farrar, François Nosten, Nicholas P.J. Day, Nicholas J. White
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/21508

To determine the optimum duration of follow-up for the assessment of drug efficacy against Plasmodium falciparum malaria, 96 trial arms from randomized controlled trials (RCTs) with follow-up of 28 days or longer that were conducted between 1990 and 2003 were analyzed. These trials enrolled 13,772 p...