Early markers of HIV-1 disease progression in a prospective cohort of seroconverters in Bangkok, Thailand: Implications for vaccine trials

• Main Authors: Kate Buchacz, Dale J. Hu, Suphak Vanichseni, Philip A. Mock, Thanyanan Chaowanachan, La Ong Srisuwanvilai, Roman Gvetadze, Frits Van Griensven, Jordan W. Tappero, Dwip Kitayaporn, Jaranit Kaewkungwal, Kachit Choopanya, Timothy D. Mastro
• Other Authors: Centers for Disease Control and Prevention
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/21618
• Institution: Mahidol University

Background: Some candidate HIV-1 vaccines may not prevent HIV-1 infection but may alter the course of disease. Surrogate endpoints based on early laboratory makers in HIV-1-infected persons who are antiretroviral therapy (ART)-naive will be useful for evaluating vaccine efficacy in slowing disease p...