Antimalarial drug resistance
Malaria, the most prevalent and most pernicious parasitic disease of humans, is estimated to kill between one and two million people, mainly children, each year. Resistance has emerged to all classes of antimalarial drugs except the artemisinins and is responsible for a recent increase in malaria-re...
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th-mahidol.217472018-07-24T10:54:48Z Antimalarial drug resistance Nicholas J. White Mahidol University Churchill Hospital Medicine Malaria, the most prevalent and most pernicious parasitic disease of humans, is estimated to kill between one and two million people, mainly children, each year. Resistance has emerged to all classes of antimalarial drugs except the artemisinins and is responsible for a recent increase in malaria-related mortality, particularly in Africa. The de novo emergence of resistance can be prevented by the use of antimalarial drug combinations. Artemisinin-derivative combinations are particularly effective, since they act rapidly and are well tolerated and highly effective. Widespread use of these drugs could roll back malaria. 2018-07-24T03:54:48Z 2018-07-24T03:54:48Z 2004-01-01 Review Journal of Clinical Investigation. Vol.113, No.8 (2004), 1084-1092 10.1172/JCI21682 00219738 2-s2.0-2142659388 https://repository.li.mahidol.ac.th/handle/123456789/21747 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=2142659388&origin=inward |
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Mahidol University |
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Asia |
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Thailand Thailand |
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Medicine |
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Medicine Nicholas J. White Antimalarial drug resistance |
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Malaria, the most prevalent and most pernicious parasitic disease of humans, is estimated to kill between one and two million people, mainly children, each year. Resistance has emerged to all classes of antimalarial drugs except the artemisinins and is responsible for a recent increase in malaria-related mortality, particularly in Africa. The de novo emergence of resistance can be prevented by the use of antimalarial drug combinations. Artemisinin-derivative combinations are particularly effective, since they act rapidly and are well tolerated and highly effective. Widespread use of these drugs could roll back malaria. |
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Mahidol University |
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Mahidol University Nicholas J. White |
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Review |
| author |
Nicholas J. White |
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Nicholas J. White |
| title |
Antimalarial drug resistance |
| title_short |
Antimalarial drug resistance |
| title_full |
Antimalarial drug resistance |
| title_fullStr |
Antimalarial drug resistance |
| title_full_unstemmed |
Antimalarial drug resistance |
| title_sort |
antimalarial drug resistance |
| publishDate |
2018 |
| url |
https://repository.li.mahidol.ac.th/handle/123456789/21747 |
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1763491843659530240 |