The thalassemic red cell membrane.

• Main Authors: P. Wilairat, A. Kittikalayawong, S. Chaicharoen
• Other Authors: Mahidol University
• Format: Review
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/22329

The underlying cause of pathology in thalassemia is the premature destruction of red cells, both in the bone marrow and by the reticuloendothelial system. It is generally accepted that the presence of unpaired excess globin chains is the primary circumstance leading to such membrane alterations as o...