High-dose mefloquine in the treatment of multidrug-resistant falciparum malaria

The therapeutic efficacy and toxicity of a high-dose (25 mg/kg) mefloquine regimen (M25) and the currently recommended regimen of 15 mg/kg (Ml5) were compared in 199 patients with acute falciparum malaria in an area with deteriorating multidrug resistance on the Thai-Burmese border. The clinical and...

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Main Authors: F. O. ter Kuile, F. Nosten, M. Thieren, C. Luxemburger, M. D. Edstein, T. Chongsuphajaisiddhi, L. Phaipun, H. K. Webster, N. J. White
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/22504
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Institution: Mahidol University