Graves' disease complicating pregnancy

During the 12-yr period from 1981 to 1992, over 85,000 deliveries at Ramathibodi Hospital from 114 pregnancies (prevalence 0.1%) in 110 patients were complicated by Graves' disease. The diagnosis was made following conception in 52 per cent. Medical treatment with propylthiouracil was the main...

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Main Authors: W. Phuapradit, R. Rajatanavin, N. Saropala, S. Hotrakit
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/22626
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spelling th-mahidol.226262018-08-10T15:56:24Z Graves' disease complicating pregnancy W. Phuapradit R. Rajatanavin N. Saropala S. Hotrakit Mahidol University Medicine During the 12-yr period from 1981 to 1992, over 85,000 deliveries at Ramathibodi Hospital from 114 pregnancies (prevalence 0.1%) in 110 patients were complicated by Graves' disease. The diagnosis was made following conception in 52 per cent. Medical treatment with propylthiouracil was the main regimen. Maternal and perinatal outcome were related with thyroid status at delivery including thyrotoxic crisis, preeclampsia and preterm deliveries. There was no case of fetal goitre, hyperthyroidism, but fetal hypothyroidism occurred in 12.2 per cent which calls for close monitoring of antithyroid drug dosage and close neonatal-infant follow-up. 2018-08-10T08:56:24Z 2018-08-10T08:56:24Z 1993-12-01 Article Journal of the Medical Association of Thailand. Vol.76, No.7 (1993), 380-384 01252208 2-s2.0-0027723990 https://repository.li.mahidol.ac.th/handle/123456789/22626 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0027723990&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
W. Phuapradit
R. Rajatanavin
N. Saropala
S. Hotrakit
Graves' disease complicating pregnancy
description During the 12-yr period from 1981 to 1992, over 85,000 deliveries at Ramathibodi Hospital from 114 pregnancies (prevalence 0.1%) in 110 patients were complicated by Graves' disease. The diagnosis was made following conception in 52 per cent. Medical treatment with propylthiouracil was the main regimen. Maternal and perinatal outcome were related with thyroid status at delivery including thyrotoxic crisis, preeclampsia and preterm deliveries. There was no case of fetal goitre, hyperthyroidism, but fetal hypothyroidism occurred in 12.2 per cent which calls for close monitoring of antithyroid drug dosage and close neonatal-infant follow-up.
author2 Mahidol University
author_facet Mahidol University
W. Phuapradit
R. Rajatanavin
N. Saropala
S. Hotrakit
format Article
author W. Phuapradit
R. Rajatanavin
N. Saropala
S. Hotrakit
author_sort W. Phuapradit
title Graves' disease complicating pregnancy
title_short Graves' disease complicating pregnancy
title_full Graves' disease complicating pregnancy
title_fullStr Graves' disease complicating pregnancy
title_full_unstemmed Graves' disease complicating pregnancy
title_sort graves' disease complicating pregnancy
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/22626
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