Evidence of vitamin K deficiency in cord blood.
The prevalence of vitamin K deficiency in the newborns delivered at Siriraj Hospital was studied. The prolongation of one stage prothrombin time and the presence of PIVKA-II (non carboxylated prothrombin antigen) in cord blood were interpreted as the secondary change from vitamin K deficiency state....
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th-mahidol.226302018-08-10T15:56:30Z Evidence of vitamin K deficiency in cord blood. C. Mahasandana P. Pung-amritt S. Yodthong V. Suvatte Mahidol University Medicine The prevalence of vitamin K deficiency in the newborns delivered at Siriraj Hospital was studied. The prolongation of one stage prothrombin time and the presence of PIVKA-II (non carboxylated prothrombin antigen) in cord blood were interpreted as the secondary change from vitamin K deficiency state. The most reliable method to diagnose vitamin K deficiency is the detection of vitamin K level in plasma which is not yet available in Thailand. Although the prevalence of vitamin K deficiency in the newborns from our data is not high, only 0.6%, it is shown that some of the apparently normal newborn infants may have bleeding problem from vitamin K deficiency in both newborn and early infancy periods. So, the correction of this deficiency by administration of vitamin K to all newborns is appropriate and reasonable decision. 2018-08-10T08:56:30Z 2018-08-10T08:56:30Z 1993-12-01 Article The Southeast Asian journal of tropical medicine and public health. Vol.24 Suppl 1, (1993), 116-120 01251562 2-s2.0-0027903403 https://repository.li.mahidol.ac.th/handle/123456789/22630 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0027903403&origin=inward |
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Medicine C. Mahasandana P. Pung-amritt S. Yodthong V. Suvatte Evidence of vitamin K deficiency in cord blood. |
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The prevalence of vitamin K deficiency in the newborns delivered at Siriraj Hospital was studied. The prolongation of one stage prothrombin time and the presence of PIVKA-II (non carboxylated prothrombin antigen) in cord blood were interpreted as the secondary change from vitamin K deficiency state. The most reliable method to diagnose vitamin K deficiency is the detection of vitamin K level in plasma which is not yet available in Thailand. Although the prevalence of vitamin K deficiency in the newborns from our data is not high, only 0.6%, it is shown that some of the apparently normal newborn infants may have bleeding problem from vitamin K deficiency in both newborn and early infancy periods. So, the correction of this deficiency by administration of vitamin K to all newborns is appropriate and reasonable decision. |
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Mahidol University |
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Mahidol University C. Mahasandana P. Pung-amritt S. Yodthong V. Suvatte |
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Article |
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C. Mahasandana P. Pung-amritt S. Yodthong V. Suvatte |
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C. Mahasandana |
title |
Evidence of vitamin K deficiency in cord blood. |
title_short |
Evidence of vitamin K deficiency in cord blood. |
title_full |
Evidence of vitamin K deficiency in cord blood. |
title_fullStr |
Evidence of vitamin K deficiency in cord blood. |
title_full_unstemmed |
Evidence of vitamin K deficiency in cord blood. |
title_sort |
evidence of vitamin k deficiency in cord blood. |
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2018 |
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https://repository.li.mahidol.ac.th/handle/123456789/22630 |
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