Beijing genotype of Mycobacterium tuberculosis is significantly associated with human immunodeficiency virus infection and multidrug resistance in cases of tuberculous meningitis

• Main Authors: Maxine Caws, Guy Thwaites, Kasia Stepniewska, Nguyen Thi Ngoc Lan, Nguyen Thi Hong Duyen, Nguyen Thi Phuong, Mai Nguyet Thu Huyen, Phan Minh Duy, Tran Huu Loc, Tran Thi Hong Chau, Dick Van Soolingen, Kristin Kremer, Nguyen Vinh Van Chau, Nguyen Tran Chinh, Jeremy Farrar
• Other Authors: UCL
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/23296
• Institution: Mahidol University

Multidrug-resistant tuberculous meningitis is fatal without rapid diagnosis and use of second-line therapy. It is more common in human immunodeficiency virus (HIV)-positive patients. Beijing genotype strains of Mycobacterium tuberculosis are associated with drug resistance, particularly multidrug re...