Early treatment failure in severe malaria resulting from abnormally low plasma quinine concentrations

Early treatment failure in severe malaria resulting from abnormally low plasma quinine concentrations

A patient admitted with severe Plasmodium falciparum malaria in western Thailand had an early treatment failure with quinine, despite full dosing. Plasma quinine concentrations were subtherapeutic. Abnormal quinine pharmacokinetics may explain sporadic reports of quinine treatment failures in severe...

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Bibliographic Details
Main Authors: Paul N. Newton, Steven Ward, Brian J. Angus, Wirongrong Chierakul, Arjen Dondorp, Ronnatrai Ruangveerayuth, Kamolrat Silamut, Pramote Teerapong, Yupin Suputtamongkol, Sornchai Looareesuwan, Nicholas J. White
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Immunology and Microbiology
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/23368
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/23368

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