Azithromycin combination therapy with artesunate or quinine for the treatment of uncomplicated Plasmodium falciparum malaria in adults: A randomized, phase 2 clinical trial in Thailand

• Main Authors: Harald Noedl, Srivicha Krudsood, Kobsiri Chalermratana, Udomsak Silachamroon, Wattana Leowattana, Noppadon Tangpukdee, Sornchai Looareesuwan, Robert Scott Miller, Mark Fukuda, Krisada Jongsakul, Sabaithip Sriwichai, Jacqueline Rowan, Helen Bhattacharyya, Colin Ohrt, Charles Knirsch
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/23474

Background. Because antimalarial drug resistance is spreading, there is an urgent need for new combination treatments for malaria, which kills >1 million people every year. Azithromycin is a macrolide antibiotic that is particularly attractive as an antimalarial because of its safety in children...