Involvement of c-Met/Hepatocyte Growth Factor Pathway in Cholangiocarcinoma Cell Invasion and Its Therapeutic Inhibition With Small Interfering RNA Specific for c-Met

• Main Authors: Kawin Leelawat, Surang Leelawat, Panada Tepaksorn, Panthip Rattanasinganchan, Anicha Leungchaweng, Rutaiwan Tohtong, Prasert Sobhon
• Other Authors: Rajavithi Hospital
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/23510
• Institution: Mahidol University

Background: Hepatocyte growth factor receptor (c-Met) plays an important role in many functions of cancer cells. We examined the roles of c-Met and its downstream signaling molecules in cholangiocarcinoma cell lines RMCCA1 and HuCCA1. Materials and methods: The expression of c-Met and their signalin...