Epstein-Barr virus associated lymphoepithelial carcinoma of the parotid gland; a clinicopathological report of three cases

Lymphoepithelial carcinoma is a relatively uncommon malignant tumor of the salivary gland demonstrating malignant epithelial cells with dense lymphoid stroma. The authors report three cases of lymphoepithelial carcinoma associated with Epstein-Barr virus of the right parotid gland with clinically pr...

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Main Authors: Noppadol Larbcharoensub, Nattha Tubtong Cert, Veeraphol Praneetvatakul, Atcharaporn Pongtippan, Juvady Leopairat, Vorachai Sirikulchayanonta
Other Authors: Mahidol University
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Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/23536
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spelling th-mahidol.235362018-08-20T14:09:25Z Epstein-Barr virus associated lymphoepithelial carcinoma of the parotid gland; a clinicopathological report of three cases Noppadol Larbcharoensub Nattha Tubtong Cert Veeraphol Praneetvatakul Atcharaporn Pongtippan Juvady Leopairat Vorachai Sirikulchayanonta Mahidol University Medicine Lymphoepithelial carcinoma is a relatively uncommon malignant tumor of the salivary gland demonstrating malignant epithelial cells with dense lymphoid stroma. The authors report three cases of lymphoepithelial carcinoma associated with Epstein-Barr virus of the right parotid gland with clinically presenting as painless, gradual enlargement of the preauricular mass. The histopathologic examination of the parotid gland is characterized by malignant epithelial cells with dense lymphoid stroma. Immunohistochemical stains show positive reactivity to cytokeratin and p53 in malignant epithelial cells. In situ hybridization of the Epstein-Barr virus-encoded Ribonucleic acid shows positivity in malignant epithelial cells. Clinical and pathologic features with relevant literatures are discussed. These are the first reported cases of primary parotid lymphoepithelial carcinoma associated with Epstein-Barr virus infection in Thailand and Southeast Asia. 2018-08-20T07:09:25Z 2018-08-20T07:09:25Z 2006-10-11 Article Journal of the Medical Association of Thailand. Vol.89, No.9 (2006), 1536-1541 01252208 01252208 2-s2.0-33749439302 https://repository.li.mahidol.ac.th/handle/123456789/23536 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33749439302&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
Noppadol Larbcharoensub
Nattha Tubtong Cert
Veeraphol Praneetvatakul
Atcharaporn Pongtippan
Juvady Leopairat
Vorachai Sirikulchayanonta
Epstein-Barr virus associated lymphoepithelial carcinoma of the parotid gland; a clinicopathological report of three cases
description Lymphoepithelial carcinoma is a relatively uncommon malignant tumor of the salivary gland demonstrating malignant epithelial cells with dense lymphoid stroma. The authors report three cases of lymphoepithelial carcinoma associated with Epstein-Barr virus of the right parotid gland with clinically presenting as painless, gradual enlargement of the preauricular mass. The histopathologic examination of the parotid gland is characterized by malignant epithelial cells with dense lymphoid stroma. Immunohistochemical stains show positive reactivity to cytokeratin and p53 in malignant epithelial cells. In situ hybridization of the Epstein-Barr virus-encoded Ribonucleic acid shows positivity in malignant epithelial cells. Clinical and pathologic features with relevant literatures are discussed. These are the first reported cases of primary parotid lymphoepithelial carcinoma associated with Epstein-Barr virus infection in Thailand and Southeast Asia.
author2 Mahidol University
author_facet Mahidol University
Noppadol Larbcharoensub
Nattha Tubtong Cert
Veeraphol Praneetvatakul
Atcharaporn Pongtippan
Juvady Leopairat
Vorachai Sirikulchayanonta
format Article
author Noppadol Larbcharoensub
Nattha Tubtong Cert
Veeraphol Praneetvatakul
Atcharaporn Pongtippan
Juvady Leopairat
Vorachai Sirikulchayanonta
author_sort Noppadol Larbcharoensub
title Epstein-Barr virus associated lymphoepithelial carcinoma of the parotid gland; a clinicopathological report of three cases
title_short Epstein-Barr virus associated lymphoepithelial carcinoma of the parotid gland; a clinicopathological report of three cases
title_full Epstein-Barr virus associated lymphoepithelial carcinoma of the parotid gland; a clinicopathological report of three cases
title_fullStr Epstein-Barr virus associated lymphoepithelial carcinoma of the parotid gland; a clinicopathological report of three cases
title_full_unstemmed Epstein-Barr virus associated lymphoepithelial carcinoma of the parotid gland; a clinicopathological report of three cases
title_sort epstein-barr virus associated lymphoepithelial carcinoma of the parotid gland; a clinicopathological report of three cases
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/23536
_version_ 1763496987318026240