Transmission-blocking activities of quinine, primaquine, and artesunate

• Main Authors: Kesinee Chotivanich, Jetsumon Sattabongkot, Rachanee Udomsangpetch, Sornchai Looareesuwan, Nicholas P.J. Day, Russell E. Coleman, Nicholas J. White
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/23735

The infectivity of Plasmodium falciparum gametocytes after exposure in vitro to quinine, artesunate, and primaquine was assessed in Anopheles dims, a major vector of malaria in Southeast Asia. Mature gametocytes (stage 5) of a Thai isolate of P. falciparum were exposed to the drugs for 24 h in vitro...