International collaborative survey on epidemiology of hepatitis E virus in 11 countries
We conducted seroepidemiological studies on antibody prevalence to hepatitis E virus (HEV) in 5,233 sera from 11 countries to ascertain the present state of HEV infection on a global basis. The prevalence of anti-HEV IgG increased with age in these tested countries, but the rate of antibody positivi...
Saved in:
Main Authors: | , , , , , , , , , , , , , , , , , , |
---|---|
Other Authors: | |
Format: | Review |
Published: |
2018
|
Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/23877 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Mahidol University |
id |
th-mahidol.23877 |
---|---|
record_format |
dspace |
spelling |
th-mahidol.238772018-08-20T14:22:23Z International collaborative survey on epidemiology of hepatitis E virus in 11 countries Kenji Abe Tian Cheng Li Xin Ding Khin Maung Win Pradeep Krishna Shrestha Vo Xuan Quang Trinh Thi Ngoc Teresa Casanovas Taltavull Andrei V. Smirnov Vasily F. Uchaikin Pairoj Luengrojanakul Hongxi Gu Abdel Rahman El-Zayadi Alfred M. Prince Kaoru Kikuchi Naohiko Masaki Ayano Inui Tetsutaro Sata Naokazu Takeda National Institute of Infectious Diseases Yangon General Hospital Tribhuvan University Teaching Hospital Cho Ray Hospital Bach Mai Hospital Hospital Universitari de Bellvitge Pirogov Russian National Research Medical University (RNRMU) Mahidol University Harbin Medical University Cairo Liver Center New York Blood Center Okinawa Chubu Hospital National Center for Global Health and Medicine International University of Health and Welfare Medicine We conducted seroepidemiological studies on antibody prevalence to hepatitis E virus (HEV) in 5,233 sera from 11 countries to ascertain the present state of HEV infection on a global basis. The prevalence of anti-HEV IgG increased with age in these tested countries, but the rate of antibody positivity was over 20% in the 16-30 year-old group in most of the participating countries, except for Japan, the USA, and Spain. Of patients with acute hepatitis of unknown etiology from Nepal, 56% (14/25) were positive for the IgM class of anti-HEV antibody. In addition, HEV RNAs in the serum from 3 Nepali patients who had the IgM antibody were detected by nested PCR and all of the HEV genes isolated belonged to genotype 1. Our results indicate that HEV is spreading worldwide, not only in developing countries, but also in more industrialized countries than previously thought. 2018-08-20T07:22:23Z 2018-08-20T07:22:23Z 2006-01-01 Review Southeast Asian Journal of Tropical Medicine and Public Health. Vol.37, No.1 (2006), 90-95 01251562 2-s2.0-33744467382 https://repository.li.mahidol.ac.th/handle/123456789/23877 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33744467382&origin=inward |
institution |
Mahidol University |
building |
Mahidol University Library |
continent |
Asia |
country |
Thailand Thailand |
content_provider |
Mahidol University Library |
collection |
Mahidol University Institutional Repository |
topic |
Medicine |
spellingShingle |
Medicine Kenji Abe Tian Cheng Li Xin Ding Khin Maung Win Pradeep Krishna Shrestha Vo Xuan Quang Trinh Thi Ngoc Teresa Casanovas Taltavull Andrei V. Smirnov Vasily F. Uchaikin Pairoj Luengrojanakul Hongxi Gu Abdel Rahman El-Zayadi Alfred M. Prince Kaoru Kikuchi Naohiko Masaki Ayano Inui Tetsutaro Sata Naokazu Takeda International collaborative survey on epidemiology of hepatitis E virus in 11 countries |
description |
We conducted seroepidemiological studies on antibody prevalence to hepatitis E virus (HEV) in 5,233 sera from 11 countries to ascertain the present state of HEV infection on a global basis. The prevalence of anti-HEV IgG increased with age in these tested countries, but the rate of antibody positivity was over 20% in the 16-30 year-old group in most of the participating countries, except for Japan, the USA, and Spain. Of patients with acute hepatitis of unknown etiology from Nepal, 56% (14/25) were positive for the IgM class of anti-HEV antibody. In addition, HEV RNAs in the serum from 3 Nepali patients who had the IgM antibody were detected by nested PCR and all of the HEV genes isolated belonged to genotype 1. Our results indicate that HEV is spreading worldwide, not only in developing countries, but also in more industrialized countries than previously thought. |
author2 |
National Institute of Infectious Diseases |
author_facet |
National Institute of Infectious Diseases Kenji Abe Tian Cheng Li Xin Ding Khin Maung Win Pradeep Krishna Shrestha Vo Xuan Quang Trinh Thi Ngoc Teresa Casanovas Taltavull Andrei V. Smirnov Vasily F. Uchaikin Pairoj Luengrojanakul Hongxi Gu Abdel Rahman El-Zayadi Alfred M. Prince Kaoru Kikuchi Naohiko Masaki Ayano Inui Tetsutaro Sata Naokazu Takeda |
format |
Review |
author |
Kenji Abe Tian Cheng Li Xin Ding Khin Maung Win Pradeep Krishna Shrestha Vo Xuan Quang Trinh Thi Ngoc Teresa Casanovas Taltavull Andrei V. Smirnov Vasily F. Uchaikin Pairoj Luengrojanakul Hongxi Gu Abdel Rahman El-Zayadi Alfred M. Prince Kaoru Kikuchi Naohiko Masaki Ayano Inui Tetsutaro Sata Naokazu Takeda |
author_sort |
Kenji Abe |
title |
International collaborative survey on epidemiology of hepatitis E virus in 11 countries |
title_short |
International collaborative survey on epidemiology of hepatitis E virus in 11 countries |
title_full |
International collaborative survey on epidemiology of hepatitis E virus in 11 countries |
title_fullStr |
International collaborative survey on epidemiology of hepatitis E virus in 11 countries |
title_full_unstemmed |
International collaborative survey on epidemiology of hepatitis E virus in 11 countries |
title_sort |
international collaborative survey on epidemiology of hepatitis e virus in 11 countries |
publishDate |
2018 |
url |
https://repository.li.mahidol.ac.th/handle/123456789/23877 |
_version_ |
1763497994001317888 |