Src-family kinase-dependent disruption of endothelial barrier function by Plasmodium falciparum merozoite proteins

• Main Authors: Mark R. Gillrie, Gowdahalli Krishnegowda, Kristine Lee, Andre G. Buret, Stephen M. Robbins, S. Looareesuwan, D. Channe Gowda, May Ho
• Other Authors: University of Calgary
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/24094
• Institution: Mahidol University

Pulmonary complication in severe Plasmodium falciparum malaria is manifested as a prolonged impairment of gas transfer or the more severe acute respiratory distress syndrome (ARDS). In either clinical presentation, vascular permeability is a major component of the pathologic process. In this report,...