Mitochondrial and nuclear p53 localization in cardiomyocytes: Redox modulation by doxorubicin (Adriamycin)?

Mitochondrial and nuclear p53 localization in cardiomyocytes: Redox modulation by doxorubicin (Adriamycin)?

Reactive oxygen (ROS) and nitrogen species (RNS) generation have been proposed to be an important mechanism of doxorubicin (Adriamycin; ADR)-induced cardiotoxicity and cardiomyocyte apoptosis, processes that may be mediated by p53 protein. We note that ADR treatment resulted in increased levels of p...

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Bibliographic Details
Main Authors: Ramaneeya Nithipongvanitch, Wanida Ittarat, Marsha P. Cole, Jitbanjong Tangpong, Daret K. St. Clair, Terry D. Oberley
Other Authors: University of Wisconsin School of Medicine and Public Health
Format: Review
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/24172
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/24172

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