The genotypes of GYPA and GYPB carrying the MNSs antigens are not associated with cerebral malaria

• Main Authors: Izumi Naka, Jun Ohashi, Jintana Patarapotikul, Hathairad Hananantachai, Polrat Wilairatana, Sornchai Looareesuwan, Katsushi Tokunaga
• Other Authors: University of Tokyo
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/24200
• Institution: Mahidol University

Plasmodium falciparum invades erythrocytes via several routes using different red blood cell receptors that include glycophorin A (GYPA) and glycophorin B (GYPB). GYPA has two codominant alleles, i.e., M and N, that correspond to the M and N antigens, which differ by two amino acids (S1L, G5E); the...