Regulation of Ca2+ mobilization by prolactin in mammary gland cells: Possible role of secretory pathway Ca2+-ATPase type 2

• Main Authors: Utchariya Anantamongkol, Haruo Takemura, Tuangporn Suthiphongchai, Nateetip Krishnamra, Yoshiyuki Horio
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/24265

Regulatory role of prolactin (PRL) on Ca2+mobilization in human mammary gland cell line MCF-7 was examined. Direct addition of PRL did not affect cytoplasmic Ca2+concentration ([Ca2+]i); however, treatment with PRL for 24 h significantly decreased the peak level and duration time of [Ca2+]ielevation...