Phase transfer bioconversion of penicillin G into 6-APA by immobilized penicillin acylase in recycling aqueous two-phase systems with a light-sensitive copolymer

Immobilized penicillin acylase was used for bioconversion of penicillin G into 6-APA in aqueous two-phase systems consisted of a light-sensitive polymer (PNBC 300000) and Dextran 20000. Partition coefficients of 6-APA was found to be about 8.4 in the presence of 50 mmol/L KCl. Results of enzyme kine...

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Bibliographic Details
Main Authors: Ke Ming Jin, Xue Jun Cao, Ying Ping Zhuang, Ju Chu, Si Liang Zhang, Duerasor Orawan
Other Authors: East China University of Science and Technology
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/24315
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Institution: Mahidol University