Combined molecular and clinical assessment of Plasmodium falciparum antimalarial drug resistance in the Lao People's Democratic Republic (Laos)

• Main Authors: Mayfong Mayxay, Shalini Nair, Dan Sudimack, Mallika Imwong, Naowarat Tanomsing, Tiengkham Pongvongsa, Samlane Phompida, Rattanaxay Phetsouvanh, Nicholas J. White, Tim J.C. Anderson, Paul N. Newton
• Other Authors: Mahosot Hospital
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/24534
• Institution: Mahidol University

Molecular markers provide a rapid and relatively inexpensive approach for assessing antimalarial drug susceptibility. We collected 884 Plasmodium falciparum-infected blood samples from 17 Lao provinces. Each sample was genotyped for 11 codons in the chloroquine resistance transporter (pfcrt), dihydr...