Dengue virus (DENV) antibody-dependent enhancement of infection upregulates the production of anti-inflammatory cytokines, but suppresses anti-DENV free radical and pro-inflammatory cytokine production, in THP-1 cells

The immunopathogenesis of dengue haemorrhagic fever and dengue shock syndrome is thought to be mediated by a variety of host factors. Enhancing antibodies are one of the key regulating molecules. These antibodies, via anti body-dependent enhancement (ADE) of infection, are able to facilitate dengue...

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Bibliographic Details
Main Authors: Takol Chareonsirisuthigul, Siripen Kalayanarooj, Sukathida Ubol
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/24583
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Institution: Mahidol University