Reduction of parasite levels in patients with uncomplicated malaria by treatment with HE2000

• Main Authors: James M. Frincke, Dwight R. Stickney, Nanette Onizuka-Handa, Armando Garsd, Christopher Reading, Srivicha Krudsood, Polrat Wilairatana, Sornchai Looareesuwan
• Other Authors: Hollis-Eden Pharmaceuticals, Inc.
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/24585
• Institution: Mahidol University

16α-Bromoepiandrosterone (HE2000) is a synthetic androstane steroid that has immune effects in preclinical models of malaria, tuberculosis, and infection with human immunodeficiency virus. In pilot studies, 42 patients with confirmed uncomplicated Plasmodium falciparum malaria were treated with a se...