Primary hepatic clear cell myomelanocytic tumor: Case report and review of the literature

A case of hepatic clear cell myomelanocytic tumor in a 31-year-old woman presenting clinically with abdominal pain is reported. Histopathologic examination showed a lesion characterized by a population of large epithelioid cells with clear or eosinophilic granular cytoplasm, rich in glycogen. Immuno...

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Main Authors: Noppadol Larbcharoensub, Patcharee Karnsombut, Janjira Jatchavala, Yodying Wasutit, Prawat Nitiyanant
其他作者: Mahidol University
格式: Article
出版: 2018
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在線閱讀:https://repository.li.mahidol.ac.th/handle/123456789/24640
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機構: Mahidol University
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總結:A case of hepatic clear cell myomelanocytic tumor in a 31-year-old woman presenting clinically with abdominal pain is reported. Histopathologic examination showed a lesion characterized by a population of large epithelioid cells with clear or eosinophilic granular cytoplasm, rich in glycogen. Immunohistochemically, the tumor cells were positive for HMB-45, Melan-A and muscle-specific actin, but negative for epithelial markers, desmin, S-100 protein, and neuroendocrine markers. Ultrastructurally, the tumor cells had abundant glycogen, well-developed rough endoplasmic reticulum, microtubules and aberrant melanosomes. Clinical and pathologic features with a brief review of the relevant literature for hepatic CCMMT as a variant of perivascular epithelioid cell tumor (PEComa) are discussed. Copyright © Apmis 2007.