Detection of VacA gene specific for Helicobactor pylori in hepatocellular carcinoma and cholangiocarcinoma specimens of Thai patients

Detection of VacA gene specific for Helicobactor pylori in hepatocellular carcinoma and cholangiocarcinoma specimens of Thai patients

In order to investigate and compare the presence of Helicobacter pylori VacA in primary liver cancer specimens (12 hepatocellular carcinoma and 6 cholangiocarcinoma) and control liver specimens (7 non-primary liver cancer) from Thai patients who underwent liver resection, H. pylori VacA gene was ass...

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Main Authors: Kawin Leelawat, Nithikoon Suksumek, Surang Leelawat, Usa Lek-Uthai
Other Authors: Rajavithi Hospital
Format: Article
Published: 2018
Subjects:
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/24771
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spelling th-mahidol.247712018-08-24T09:01:39Z Detection of VacA gene specific for Helicobactor pylori in hepatocellular carcinoma and cholangiocarcinoma specimens of Thai patients Kawin Leelawat Nithikoon Suksumek Surang Leelawat Usa Lek-Uthai Rajavithi Hospital Vajira Hospital Rangsit University Mahidol University Medicine In order to investigate and compare the presence of Helicobacter pylori VacA in primary liver cancer specimens (12 hepatocellular carcinoma and 6 cholangiocarcinoma) and control liver specimens (7 non-primary liver cancer) from Thai patients who underwent liver resection, H. pylori VacA gene was assayed in extracted DNA by real-time polymerase chain reaction. The selected amplicons revealed high homology compared with H. pylori VacA sequence. H. pylori VacA gene was detected in all primary liver cancer specimens and in 71% (5/7) of control liver specimens. 2018-08-24T02:01:39Z 2018-08-24T02:01:39Z 2007-09-01 Article Southeast Asian Journal of Tropical Medicine and Public Health. Vol.38, No.5 (2007), 881-885 01251562 2-s2.0-35348979076 https://repository.li.mahidol.ac.th/handle/123456789/24771 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=35348979076&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
Kawin Leelawat
Nithikoon Suksumek
Surang Leelawat
Usa Lek-Uthai
Detection of VacA gene specific for Helicobactor pylori in hepatocellular carcinoma and cholangiocarcinoma specimens of Thai patients
description In order to investigate and compare the presence of Helicobacter pylori VacA in primary liver cancer specimens (12 hepatocellular carcinoma and 6 cholangiocarcinoma) and control liver specimens (7 non-primary liver cancer) from Thai patients who underwent liver resection, H. pylori VacA gene was assayed in extracted DNA by real-time polymerase chain reaction. The selected amplicons revealed high homology compared with H. pylori VacA sequence. H. pylori VacA gene was detected in all primary liver cancer specimens and in 71% (5/7) of control liver specimens.
author2 Rajavithi Hospital
author_facet Rajavithi Hospital
Kawin Leelawat
Nithikoon Suksumek
Surang Leelawat
Usa Lek-Uthai
format Article
author Kawin Leelawat
Nithikoon Suksumek
Surang Leelawat
Usa Lek-Uthai
author_sort Kawin Leelawat
title Detection of VacA gene specific for Helicobactor pylori in hepatocellular carcinoma and cholangiocarcinoma specimens of Thai patients
title_short Detection of VacA gene specific for Helicobactor pylori in hepatocellular carcinoma and cholangiocarcinoma specimens of Thai patients
title_full Detection of VacA gene specific for Helicobactor pylori in hepatocellular carcinoma and cholangiocarcinoma specimens of Thai patients
title_fullStr Detection of VacA gene specific for Helicobactor pylori in hepatocellular carcinoma and cholangiocarcinoma specimens of Thai patients
title_full_unstemmed Detection of VacA gene specific for Helicobactor pylori in hepatocellular carcinoma and cholangiocarcinoma specimens of Thai patients
title_sort detection of vaca gene specific for helicobactor pylori in hepatocellular carcinoma and cholangiocarcinoma specimens of thai patients
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/24771
_version_ 1763496813925498880

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