Peroral delivery of insulin using chitosan derivatives: A comparative study of polyelectrolyte nanocomplexes and nanoparticles

Polymeric delivery systems based on nanoparticles (NP) have emerged as a promising approach for peroral insulin delivery. Using a trimethyl chitosan (TMC) and a PEG-graft-TMC copolymer, polyelectrolyte complexes (PEC) and nanoparticles were prepared and their properties were compared. The amount of...

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Bibliographic Details
Main Authors: Anchalee Jintapattanakit, Varaporn B. Junyaprasert, Shirui Mao, Johannes Sitterberg, Udo Bakowsky, Thomas Kissel
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/25092
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Institution: Mahidol University