No direct hepatotoxic potential following a multiple-low dose paraquat exposure in rat as related to its bioaccumulation

• Main Authors: Varaporn Podprasart, Jutamaad Satayavivad, Suda Riengrojpitak, Prapin Wilairat, Winai Wananukul, Pranee Chavalittumrong, Songpol Chivapat, Krongtong Yoovathaworn
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/25103

Paraquat (PQ) is a well-known toxic bipyridyl herbicide commonly used in agricultural countries. Pulmonary toxicity is the main cause of death but damage to other organs has also been reported. PQ is also classified as a "direct hepatotoxicant" following an acute high dose exposure. The ev...