New cytotoxic 1-azaanthraquinones and 3-aminonaphthoquinone from the stem bark of Goniothalamus mareanii

• Main Authors: Noppamas Soonthornchareonnon, Khanit Suwanborirux, Rapepol Bavovada, Chamnan Patarapanich, John M. Cassady
• Other Authors: Chulalongkorn University
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/25277
• Institution: Mahidol University

Guided by brine shrimp toxicity and human tumor cell toxicity, fractionation of the alcoholic extract from the stem bark of Goniothalamus marcanii led to the isolation of four new 1-azaanthraquinones: marcanines B (3), C (4), D (5), and E (6), along with two known derivatives: marcanine A and dielsi...