A case-control auditory evaluation of patients treated with artemisinin derivatives for multidrug-resistant Plasmodium falciparum malaria

• Main Authors: M. Van Vugt, B. J. Angus, R. N. Price, C. Mann, J. A. Simpson, C. Poletto, Saw Eh Htoo, S. Looareesuwan, N. J. White, F. Nosten
• Other Authors: Shoklo Malaria Research Unit
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/26014
• Institution: Mahidol University

The artemisinin derivatives are now used widely in areas with multidrug- resistant Plasmodium falciparum malaria such as Southeast Asia, but concerns remain over their potential for neurotoxicity. Mice, rats, dogs, and monkeys treated with high doses of intramuscular artemether or arteether develop...