Opportunistic infections in the liver of HIV-infected patients in Thailand: A necropsy study
Liver necropsy from patients infected with human immunodeficiency virus was analyzed in 117 cases. Wide ranges of opportunistic infections were recorded in 47%. Cryptococcosis (21.4%) was the most outstanding infection, followed by tuberculosis (16.2%), cytomegalovirus (5.1%) and penicillosis (3.4%)...
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th-mahidol.261032018-09-07T16:16:00Z Opportunistic infections in the liver of HIV-infected patients in Thailand: A necropsy study Parnpen Viriyavejakul Porntip Rojanasunan Akravudh Viriyavejakul Phaiboon Punyarit Benjanee Punpoowong Vasant Khachansaksumet Mario Riganti Emsri Pongponratn Mahidol University Thailand Ministry of Public Health Phramongkutklao College of Medicine Medicine Liver necropsy from patients infected with human immunodeficiency virus was analyzed in 117 cases. Wide ranges of opportunistic infections were recorded in 47%. Cryptococcosis (21.4%) was the most outstanding infection, followed by tuberculosis (16.2%), cytomegalovirus (5.1%) and penicillosis (3.4%). Non-specific alterations of the liver tissues included fatty steatosis (49.6%), fibrosis (55.6%), portal inflammation and reactive hepatitis. Cases of chronic active and chronic passive hepatitis and one case of hepatocellular carcinoma were reported. In the infected liver, predominant pathological changes included granuloma and spotty necrosis, which were attributed to tuberculous hepatitis. Infection with Cryptococcus usually showed no associated pathological change. The sensitivity for the clinical diagnosis of Cryptococcus was 88.8% and specificity was 91.7%. For tuberculosis, sensitivity was 20% and specificity was 67.9%. 2018-09-07T09:16:00Z 2018-09-07T09:16:00Z 2000-12-01 Article Southeast Asian Journal of Tropical Medicine and Public Health. Vol.31, No.4 (2000), 663-667 01251562 2-s2.0-0034574687 https://repository.li.mahidol.ac.th/handle/123456789/26103 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0034574687&origin=inward |
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Medicine Parnpen Viriyavejakul Porntip Rojanasunan Akravudh Viriyavejakul Phaiboon Punyarit Benjanee Punpoowong Vasant Khachansaksumet Mario Riganti Emsri Pongponratn Opportunistic infections in the liver of HIV-infected patients in Thailand: A necropsy study |
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Liver necropsy from patients infected with human immunodeficiency virus was analyzed in 117 cases. Wide ranges of opportunistic infections were recorded in 47%. Cryptococcosis (21.4%) was the most outstanding infection, followed by tuberculosis (16.2%), cytomegalovirus (5.1%) and penicillosis (3.4%). Non-specific alterations of the liver tissues included fatty steatosis (49.6%), fibrosis (55.6%), portal inflammation and reactive hepatitis. Cases of chronic active and chronic passive hepatitis and one case of hepatocellular carcinoma were reported. In the infected liver, predominant pathological changes included granuloma and spotty necrosis, which were attributed to tuberculous hepatitis. Infection with Cryptococcus usually showed no associated pathological change. The sensitivity for the clinical diagnosis of Cryptococcus was 88.8% and specificity was 91.7%. For tuberculosis, sensitivity was 20% and specificity was 67.9%. |
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Mahidol University |
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Mahidol University Parnpen Viriyavejakul Porntip Rojanasunan Akravudh Viriyavejakul Phaiboon Punyarit Benjanee Punpoowong Vasant Khachansaksumet Mario Riganti Emsri Pongponratn |
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Article |
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Parnpen Viriyavejakul Porntip Rojanasunan Akravudh Viriyavejakul Phaiboon Punyarit Benjanee Punpoowong Vasant Khachansaksumet Mario Riganti Emsri Pongponratn |
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Parnpen Viriyavejakul |
title |
Opportunistic infections in the liver of HIV-infected patients in Thailand: A necropsy study |
title_short |
Opportunistic infections in the liver of HIV-infected patients in Thailand: A necropsy study |
title_full |
Opportunistic infections in the liver of HIV-infected patients in Thailand: A necropsy study |
title_fullStr |
Opportunistic infections in the liver of HIV-infected patients in Thailand: A necropsy study |
title_full_unstemmed |
Opportunistic infections in the liver of HIV-infected patients in Thailand: A necropsy study |
title_sort |
opportunistic infections in the liver of hiv-infected patients in thailand: a necropsy study |
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2018 |
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https://repository.li.mahidol.ac.th/handle/123456789/26103 |
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1763497533532798976 |