Antifungal drug combinations for Cryptococcus neoformans and Prototheca spp.
Seventy-one isolates of Cryptococcus neoformans and 5 isolates of Prototheca spp. were tested for in vitro susceptibility against amphotericin B alone and against the combination of amphotericin B with each clinically relevant concentration of flucytosine (5-FC) and rifampin by broth dilution method...
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th-mahidol.263442018-09-07T16:24:24Z Antifungal drug combinations for Cryptococcus neoformans and Prototheca spp. Somboon Srimuang Angkana Chaiprasert Deja Tanphaichitra Chularut Prariyachatigul Watcharin Rungsipanuratn Faculty of Medicine, Ramathibodi Hospital, Mahidol University Khon Kaen University Mahidol University Prince of Songkla University Medicine Seventy-one isolates of Cryptococcus neoformans and 5 isolates of Prototheca spp. were tested for in vitro susceptibility against amphotericin B alone and against the combination of amphotericin B with each clinically relevant concentration of flucytosine (5-FC) and rifampin by broth dilution methods. The combinations of amphotericin B and rifampin produced greater effect on reduction of the minimal inhibition concentration (MIC) of amphotericin B than did either drug used individually. Flucytosine combined with amphotericin B produced little or no reduction of the MIC compared with amphotericin B alone. 2018-09-07T09:24:24Z 2018-09-07T09:24:24Z 2000-01-01 Article Journal of the Medical Association of Thailand. Vol.83, No.1 (2000), 57-60 01252208 2-s2.0-0034099761 https://repository.li.mahidol.ac.th/handle/123456789/26344 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0034099761&origin=inward |
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Medicine Somboon Srimuang Angkana Chaiprasert Deja Tanphaichitra Chularut Prariyachatigul Watcharin Rungsipanuratn Antifungal drug combinations for Cryptococcus neoformans and Prototheca spp. |
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Seventy-one isolates of Cryptococcus neoformans and 5 isolates of Prototheca spp. were tested for in vitro susceptibility against amphotericin B alone and against the combination of amphotericin B with each clinically relevant concentration of flucytosine (5-FC) and rifampin by broth dilution methods. The combinations of amphotericin B and rifampin produced greater effect on reduction of the minimal inhibition concentration (MIC) of amphotericin B than did either drug used individually. Flucytosine combined with amphotericin B produced little or no reduction of the MIC compared with amphotericin B alone. |
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Faculty of Medicine, Ramathibodi Hospital, Mahidol University |
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Faculty of Medicine, Ramathibodi Hospital, Mahidol University Somboon Srimuang Angkana Chaiprasert Deja Tanphaichitra Chularut Prariyachatigul Watcharin Rungsipanuratn |
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Article |
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Somboon Srimuang Angkana Chaiprasert Deja Tanphaichitra Chularut Prariyachatigul Watcharin Rungsipanuratn |
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Somboon Srimuang |
title |
Antifungal drug combinations for Cryptococcus neoformans and Prototheca spp. |
title_short |
Antifungal drug combinations for Cryptococcus neoformans and Prototheca spp. |
title_full |
Antifungal drug combinations for Cryptococcus neoformans and Prototheca spp. |
title_fullStr |
Antifungal drug combinations for Cryptococcus neoformans and Prototheca spp. |
title_full_unstemmed |
Antifungal drug combinations for Cryptococcus neoformans and Prototheca spp. |
title_sort |
antifungal drug combinations for cryptococcus neoformans and prototheca spp. |
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2018 |
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https://repository.li.mahidol.ac.th/handle/123456789/26344 |
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1763490234488586240 |