Effects of dietary protein intake on carnitine status in Thai men

• Main Authors: Vichai Tanphaichitr, Ratana Pakpeankitvatana
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine; Nursing
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/26473

Healthy men receiving adequate intakes of energy and fat without protein and carnitine for 14 days had significantly higher mean 24-h urinary free, acyl, and total carnitine excretions than the control subjects. Hen egg was the sole source of protein in this study and constained 7.77 μmol of carnitine/100 g. The stress stimuli due to the lack of protein and carnitine intakes were alleviated with the protein intakes of 0.35, 0.50, 0.55, 0.65, 0.70, and 0.85 g/kg/d, evidenced by the significant decreases in the 3 forms of 24-h urinary carnitine excretions. Their significantly lower in the 3 forms of 24-h urinary carnitine excretions than the control subjects with carnitine intake of 176 μmol/d were due to their limited intakes of carnitine: 12-30 μmol/d. Their significant increases in urinary acylcarnitine/total carnitine ratios indicated the utilization of carnitine in fatty acid oxidation. © 2001 Elsevier Science Inc.