Synthesis of 4-aryltetrahydroisoquinolines: Application to the synthesis of cherylline

A concise route for the synthesis of 4-aryltetrahydroisoquinolines was developed using the addition of Grignard reagents to nitrostyrene derivatives as the key step. The application to the synthesis of cherylline was described.

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Bibliographic Details
Main Authors:	Somsak Ruchirawat, Sopchok Tontoolarug, Poolsar Sahakitpichan
Other Authors:	Chulabhorn Research Institute
Format:	Article
Published:	2018
Subjects:	Chemistry Pharmacology, Toxicology and Pharmaceutics
Online Access:	https://repository.li.mahidol.ac.th/handle/123456789/26514
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Institution:	Mahidol University

id	th-mahidol.26514
record_format	dspace
spelling	th-mahidol.265142018-09-07T16:53:48Z Synthesis of 4-aryltetrahydroisoquinolines: Application to the synthesis of cherylline Somsak Ruchirawat Sopchok Tontoolarug Poolsar Sahakitpichan Chulabhorn Research Institute Mahidol University The Institute of Science and Technology for Research and Development, Mahidol University Chemistry Pharmacology, Toxicology and Pharmaceutics A concise route for the synthesis of 4-aryltetrahydroisoquinolines was developed using the addition of Grignard reagents to nitrostyrene derivatives as the key step. The application to the synthesis of cherylline was described. 2018-09-07T09:39:55Z 2018-09-07T09:39:55Z 2001-04-01 Article Heterocycles. Vol.55, No.4 (2001), 635-640 10.3987/COM-01-9167 03855414 2-s2.0-0035307110 https://repository.li.mahidol.ac.th/handle/123456789/26514 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0035307110&origin=inward
institution	Mahidol University
building	Mahidol University Library
continent	Asia
country	Thailand Thailand
content_provider	Mahidol University Library
collection	Mahidol University Institutional Repository
topic	Chemistry Pharmacology, Toxicology and Pharmaceutics
spellingShingle	Chemistry Pharmacology, Toxicology and Pharmaceutics Somsak Ruchirawat Sopchok Tontoolarug Poolsar Sahakitpichan Synthesis of 4-aryltetrahydroisoquinolines: Application to the synthesis of cherylline
description	A concise route for the synthesis of 4-aryltetrahydroisoquinolines was developed using the addition of Grignard reagents to nitrostyrene derivatives as the key step. The application to the synthesis of cherylline was described.
author2	Chulabhorn Research Institute
author_facet	Chulabhorn Research Institute Somsak Ruchirawat Sopchok Tontoolarug Poolsar Sahakitpichan
format	Article
author	Somsak Ruchirawat Sopchok Tontoolarug Poolsar Sahakitpichan
author_sort	Somsak Ruchirawat
title	Synthesis of 4-aryltetrahydroisoquinolines: Application to the synthesis of cherylline
title_short	Synthesis of 4-aryltetrahydroisoquinolines: Application to the synthesis of cherylline
title_full	Synthesis of 4-aryltetrahydroisoquinolines: Application to the synthesis of cherylline
title_fullStr	Synthesis of 4-aryltetrahydroisoquinolines: Application to the synthesis of cherylline
title_full_unstemmed	Synthesis of 4-aryltetrahydroisoquinolines: Application to the synthesis of cherylline
title_sort	synthesis of 4-aryltetrahydroisoquinolines: application to the synthesis of cherylline
publishDate	2018
url	https://repository.li.mahidol.ac.th/handle/123456789/26514
_version_	1763493511719550976

Synthesis of 4-aryltetrahydroisoquinolines: Application to the synthesis of cherylline

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