Malaria vaccine trials in a wormy world
The promising malaria vaccine candidates that have been tested in the field have, so far, yielded disappointing and, at times, conflicting results. Considerable efforts are being made to isolate new immunogenic molecules. However, the fact that most populations in malaria endemic areas are also infe...
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th-mahidol.265482018-09-07T16:43:37Z Malaria vaccine trials in a wormy world Mathieu Nacher Mahidol University Immunology and Microbiology Medicine The promising malaria vaccine candidates that have been tested in the field have, so far, yielded disappointing and, at times, conflicting results. Considerable efforts are being made to isolate new immunogenic molecules. However, the fact that most populations in malaria endemic areas are also infected by helminths appears to be overlooked. Helminth-related hyporesponsiveness to tetanus or cholera vaccines, and the interactions between malaria parasites and helminths, raise the possibility that a potent malaria vaccine will not be identified in helminth-infected populations, thus necessitating a change in vaccine trial design. 2018-09-07T09:41:05Z 2018-09-07T09:41:05Z 2001-12-01 Short Survey Trends in Parasitology. Vol.17, No.12 (2001), 563-565 10.1016/S1471-4922(01)02117-1 14714922 2-s2.0-0035698082 https://repository.li.mahidol.ac.th/handle/123456789/26548 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0035698082&origin=inward |
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Mahidol University |
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Mahidol University Library |
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Asia |
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Thailand Thailand |
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Immunology and Microbiology Medicine |
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Immunology and Microbiology Medicine Mathieu Nacher Malaria vaccine trials in a wormy world |
| description |
The promising malaria vaccine candidates that have been tested in the field have, so far, yielded disappointing and, at times, conflicting results. Considerable efforts are being made to isolate new immunogenic molecules. However, the fact that most populations in malaria endemic areas are also infected by helminths appears to be overlooked. Helminth-related hyporesponsiveness to tetanus or cholera vaccines, and the interactions between malaria parasites and helminths, raise the possibility that a potent malaria vaccine will not be identified in helminth-infected populations, thus necessitating a change in vaccine trial design. |
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Mahidol University |
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Mahidol University Mathieu Nacher |
| format |
Short Survey |
| author |
Mathieu Nacher |
| author_sort |
Mathieu Nacher |
| title |
Malaria vaccine trials in a wormy world |
| title_short |
Malaria vaccine trials in a wormy world |
| title_full |
Malaria vaccine trials in a wormy world |
| title_fullStr |
Malaria vaccine trials in a wormy world |
| title_full_unstemmed |
Malaria vaccine trials in a wormy world |
| title_sort |
malaria vaccine trials in a wormy world |
| publishDate |
2018 |
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https://repository.li.mahidol.ac.th/handle/123456789/26548 |
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1763491792889577472 |