Localization of Shiga toxins of enterohaemorrhagic Escherichia coli in kidneys of paediatric and geriatric patients with fatal haemolytic uraemic syndrome

• Main Authors: Urai Chaisri, Michio Nagata, Hisao Kurazono, Hiroshi Horie, Pongsri Tongtawe, Hideo Hayashi, Teruo Watanabe, Pramuan Tapchaisri, Manas Chongsa-Nguan, Wanpen Chaicumpa
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/26587

Haemolytic uraemic syndrome (HUS) is characterized by haemolytic anaemia, thrombocytopenia and renal failure. Infection with enterohaemorrhagic Escherichia coli (EHEC), mainly O157:H7, has been strongly implicated as the major cause of HUS in children. The pathogenesis of HUS caused by the infection...