Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children

• Main Authors: Fiona E. Lovegrove, Noppadon Tangpukdee, Robert O. Opoka, Erin I. Lafferty, Nimerta Rajwans, Michael Hawkes, Srivicha Krudsood, Sornchai Looareesuwan, Chandy C. John, W. Conrad Liles, Kevin C. Kain
• Other Authors: University Health Network University of Toronto
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/27036
• Institution: Mahidol University

Background: Limited tools exist to identify which individuals infected with Plasmodium falciparum are at risk of developing serious complications such as cerebral malaria (CM). The objective of this study was to assess serum biomarkers that differentiate between CM and non-CM, with the long-term goa...