Probability of emergence of antimalarial resistance in different stages of the parasite life cycle

• Main Authors: Wirichada Pongtavornpinyo, Ian M. Hastings, Arjen Dondorp, Lisa J. White, Richard J. Maude, Sompob Saralamba, Nicholas P. Day, Nicholas J. White, MacIej F. Boni
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/27060

Understanding the evolution of drug resistance in malaria is a central area of study at the intersection of evolution and medicine. Antimalarial drug resistance is a major threat to malaria control and directly related to trends in malaria attributable mortality. Artemisinin combination therapies (A...