Selection of LigA-binding peptides by bacterial display

• Main Authors: Chartchalerm Isarankura-Na-Ayudhya, Tanawut Tantimongcolwat, Chadinee Thippakorn, Virapong Prachayasittikul
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Computer Science; Earth and Planetary Sciences; Engineering; Materials Science; Mathematics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/27066

Leptospirosis is a severe disease of human and animals caused by pathogenic Leptospira spp. Previous findings reveal that the organisms express leptospiral immunoglobulin-like protein A (LigA) on their surfaces only in vivo, which is believed to serve as a virulence factor for host cell attachment a...