N<sup>α</sup>-tosyl-L-phenylalanine chloromethyl ketone induces caspase-dependent apoptosis in transformed human B cell lines with transcriptional down-regulation of anti-apoptotic HS1-associated protein X-1

N<sup>α</sup>-tosyl-L-phenylalanine chloromethyl ketone induces caspase-dependent apoptosis in transformed human B cell lines with transcriptional down-regulation of anti-apoptotic HS1-associated protein X-1

Nα-Tosyl-L-phenylalanine chloromethylketone (TPCK) has been widely used to investigate signal transduction pathways that are involved in gene expression and cell survival/cell death. However, contradictory effects of TPCK on apoptosis have been reported, and the underlying signaling events leading t...

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Bibliographic Details
Main Authors: Siriporn Jitkaew, Alicja Trebinska, Ewa Grzybowska, Göran Carlsson, Anders Nordström, Janne Lehtiö, Anne Sophie Fröjmark, Niklas Dahl, Bengt Fadeel
Other Authors: Karolinska University Hospital
Format: Article
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/27133
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/27133

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