Alpha-smooth muscle actin-positive fibroblasts promote biliary cell proliferation and correlate with poor survival in cholangiocarcinoma

• Main Authors: Chanisa Chuaysri, Peti Thuwajit, Anucha Paupairoj, Siri Chau-In, Tuangporn Suthiphongchai, Chanitra Thuwajit
• Other Authors: Khon Kaen University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/27196
• Institution: Mahidol University

Cancer-associated fibroblasts have been proposed to play a role in promoting carcinogenesis and tumor progression. To our knowledge, no direct evidence concerning fibroblasts in the genesis of cholangiocarcinoma (CCA) has previously been presented. This study aims to assess the value of activated fi...