RNA helicase module in an acetyltransferase that modifies a specific tRNA anticodon

• Main Authors: Sarin Chimnaronk, Tateki Suzuki, Tetsuhiro Manita, Yoshiho Ikeuchi, Min Yao, Tsutomu Suzuki, Isao Tanaka
• Other Authors: Hokkaido University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine; Neuroscience
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/27230
• Institution: Mahidol University

Post-transcriptional RNA modifications in the anticodon of transfer RNAs frequently contribute to the high fidelity of protein synthesis. In eubacteria, two genome-encoded transfer RNA (tRNA) species bear the same CAU sequence as the anticodons, which are differentiated by modified cytidines at the...