Inhibition of PI3K increases oxaliplatin sensitivity in cholangiocarcinoma cells

Background: Resistance of cholangiocarcinoma to chemotherapy is a major problem in cancer treatment. The mechanism of resistance is believed to involve phosphoinositide-3- kinase (PI3K)/Akt activation. Although the platinum-containing compound oxaliplatin has been extensively used in the treatment o...

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Bibliographic Details
Main Authors: Kawin Leelawat, Siriluck Narong, Wandee Udomchaiprasertkul, Surang Leelawat, Sumalee Tungpradubkul
Other Authors: Rajavithi Hospital
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/27299
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Institution: Mahidol University